IDENTIFIKASI SENYAWA STEROID DARI PANGSA KULIT DURIAN (Durio zibethinus)
Keywords:
durian, steroid, GC-MSAbstract
Plants are natural ingredients that are widely used as traditional medicines and have been used for a long time by the people of Indonesia, even more popular both for the purpose of health care, treatment, and beauty, one of which is the use of durian rind as an anti-cholesterol drug based on their knowledge for generations. Although it is not yet equipped with scientifically convincing data regarding the content of active compounds that make it a nutritious drug, scientific research is needed in the form of identifying the steroid compounds contained therein. This research used maceration extraction method. A total of 50 grams of durian skin share powder was soaked with 96% ethanol which was carried out for 3 days with replacement fluid. Furthermore, the identification of secondary metabolite compounds by the Gas Chromatography-Mass Spectroscopy (GC-MS) Agilent 7890A-5975C method. Based on the results of a study conducted a share of positive durian skin containing a group of steroid compounds in the form of beta-sitosterol.
Downloads
References
[2] Berges, R.R. 1995. Randomezed, Placebo-Controlled, Double Blind Clinical Trial of Betasitosterol in Patients with Benign Prostatic Hyperplasia. The Lancet 1995; 345: 1529-1532.
[3] Katzum, B. 2004. Farmakologi Dasar dan Klinik. Salemba Madika. Jakarta. Terjemahan Huriati dan Hartanto. Penerbit Buku Kedokteran EGC. Jakarta.
[4] Lestari, S., Fitmawati dan N. N. Wahibah.2011. Keanekaragaman durian (Durio zibethinus Murr) di Pulau Bengkalis berdasarkan karakter morfologi. Buletin Kebun Raya. 14 (2):29-44.
[5] Rusmiati., E. Mulyanto., S. Ashari., M. A. Widodo., dan L. Bansir. 2013. Eksplorasi, inventarisasi dan karakterisasi durian merahBanyuwangi. Prosiding Semirata FMIPA Universitas Lampung.
[6] Wholefoods. 2003. Phythosterol: Sterol, Sterolin dan β-sitosterol. www.staff.uny.ac.id. Diakses pada 1 Juni 2016.
Downloads
Published
How to Cite
Issue
Section
License
In submitting the manuscript to the journal, the authors certify that:
- They are authorized by their co-authors to enter into these arrangements.
- The work described has not been formally published before, except in the form of an abstract or as part of a published lecture, review, thesis, or overlay journal.
- That it is not under consideration for publication elsewhere,
- That its publication has been approved by all the author(s) and by the responsible authorities – tacitly or explicitly – of the institutes where the work has been carried out.
- They secure the right to reproduce any material that has already been published or copyrighted elsewhere.
- They agree to the following license and copyright agreement.
License and Copyright Agreement
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under Creative Commons Attribution License (CC BY 4.0) that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.